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September 02, 2010  
EDUCATION CENTER: Diagnostics
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  • Bernstein Test (Acid Perfusion Test)


    Overview:
    Reviewed by Dr. Richard Alweis

    The Bernstein tests whether acid reflux is the cause of chest or back pain. If results are positive, then acid reflux (heartburn) is present. If negative, you may have a heart problem that needs to be explored.

    Detailed Information:
    Before the test

    You must fast for 8-12 hours, and avoid alcohol for 24 hours. Ask your doctor if it’s okay to take medications during that time. Medications like adrenergic blockers, antacids, anti-cholinergics, corticosteroids and Reserpine can all interfere with test results.

    During the test

    The test takes about 30 minutes. Your healthcare professional will pass a thin catheter through your nose and into your esophagus. The lubricant on the tube may have a bad taste, and the feel of the tube in your throat may cause you to gag or cough. If the tube is accidentally inserted into your trachea instead of your esophagus, you will cough and it will be immediately removed.

    Two liquids will be slowly dripped into the tube: a hydrochloric acid solution, which has a low pH, and a saline solution, which has a neutral pH (a pH of 7). You will not be told which substance is being dripped at any given time. If you have gastroesophageal reflux disease (GERD, or heartburn), the acidic solution may cause chest pain. Tell your doctor if you experience discomfort. A sample of your gastric contents will be removed and sent to a laboratory for analysis.

    The Bernstein test is potentially dangerous if you have certain cardiac disorders. During the test, your heart rhythms will be closely monitored in case any problems arise.

    After the test

    You may have a sore throat after the test; a lozenge can help. You may resume your normal diet and activities immediately. Additional studies may be ordered to determine a more specific cause of your symptoms. An accurate diagnosis of GERD and its underlying cause often requires multiple tests.

    Last updated: 09-Apr-03


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