Symptoms
The most common symptoms of esophageal cancer are pain or difficulty swallowing and weight loss, while pain in the upper chest, hoarseness, coughing, indigestion, and heartburn may also indicate a problem. Heartburn has been linked to esophageal cancer primarily through the intermediary condition of Barrett's Esophagus. Prolonged exposure to acidic stomach contents (as in heartburn) can lead to the development of Barrett's Esophagus, in which the normal squamous cells change into secretory/glandular cells. These cells are much more likely to become malignant. For these reasons, the American College of Gastroenterology recommends both stomach and esophageal endoscopies for individuals with a recurring history of heartburn.

Last updated: 01-Jul-08